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The incidence is about three times higher in children than in adults.
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Calcium citrate (as tetrahydrate, 21% Ca2+): Slightlysoluble in water, but dissolves well in presence of HCl. MMP-1 (collagenase IV) is a key enzyme required for degradationof extracellular matrix (ECM) as a component of the metastatic process, in additionto its role in angiogenesis
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Ibuprofen is used as a simple analgesic andantipyretic in the same way as low dose of aspirin.It is particularly effective in dysmenorrhoea inwhich the action is clearly due to PG synthesisinhibition.
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