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Langley E et al (2002) Human SIR2 deacetylates p53 and antagonizes PML/p53-inducedcellular senescence. Intercalateddisks are present in Purkinje fibers, but they arevariable in ap-pearance and number depending on their location. Different locations may be more suitable depending on the vas-cular region of interest, particularly in patients suffering SAH where the arterial territoriesmost likely to experience vasospasm and delayed cerebral ischemia are those perfused bythe ruptured artery. Now I’d like to followup on what you were saying before they came in. The clinical manifesta-tions are those of amyotrophic weakness, atrophy, andfasciculations and signs of corticospinal tract dysfunction(weakness, spasticity) in various combinations
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